About the Joint Space Immunology Laboratory

Dr. Cyndari is an Emergency Medicine physician dedicated to improving outcomes for all her patients. The Cyndari Laboratory studies the immune response within the joint space during infectious and inflammatory arthritis.  These studies implement a unique ex-vivo system using synovial tissue from human patients. This Joint Space Analysis system (JSAS) allows research in a human model to further understand the arthritic joint space and identify new potential treatment targets.

Cyndari Lab Members

Meet the Lab Members

Learn more about the Researchers that make up the Cyndari Lab!

Funding

Our Funding

Learn more about the funding involved in helping us carry out our research!

Inflamed Knee Joint

About the Research

Learn more about the research that is done in the Cyndari Lab.

Welcoming

To trainees from diverse backgrounds and experiences

Partnership

Emergency Medicine, Immunology, Epidemiology

Novel

Human Based Tissue Assays
Lab in Hawaii

Cyndari Lab News

Check out the latest news and events happening in the Cyndari Laboratory!

UIHC

Membership to University of Iowa Holden Comprehensive Cancer Center

 In September 2025, the Joint Space Immunology Laboratory was welcomed into the UI Holden Comprehensive Cancer Center. This prestigious center joins the ranks of the nation’s premier cancer centers in a research mission to eliminate the burden of cancer. It is an honor to join the HCCC!

2025 International Lyme Conference

2025 International Conference: Lyme Borreliosis

September 2025, Dr. Karen Cyndari and KariAn Mulford will present their work at the 2025 International Conference: Lyme Borreliosis and Other Tick-Borne Diseases. Their presentation is entitled, "B. burgdorferi Infection Alters Synovial Macrophage Response in a Human ex vivo Model of Lyme Arthritis."

Events

Biology Seminar: "A live look at building and rebuilding neuronal circuitry" promotional image

Biology Seminar: "A live look at building and rebuilding neuronal circuitry"

Friday, December 5, 2025 3:30pm
Biology Building East
The Department of Biology’s seminar speaker on Friday, Dec. 5, at 3:30 p.m. is Lauren Walker, an Assistant Professor in the Department of Molecular and Systems Biology (Geisel School of Medicine) at Dartmouth College. Her seminar will be held in Kollros Auditorium (Room 101), Biology Building East (BBE). A reception with refreshments will be held in the BBE Lobby following the seminar.

Women In Micro & Immuno Coffee Hour

Monday, December 8, 2025 11:00am to 12:00pm
Carver Biomedical Research Building

Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion!

This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science.

Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.

Seminar Series: Department of Microbiology and Immunology

Tuesday, December 9, 2025 3:00pm to 4:00pm
Bowen Science Building

Each semester, we are proud to host outstanding seminar speakers. Everyone is encouraged to attend.