About the Joint Space Immunology Laboratory

Dr. Cyndari is an Emergency Medicine physician dedicated to improving outcomes for all her patients. The Cyndari Laboratory studies the immune response within the joint space during infectious and inflammatory arthritis.  These studies implement a unique ex-vivo system using synovial tissue from human patients. This Joint Space Analysis system (JSAS) allows research in a human model to further understand the arthritic joint space and identify new potential treatment targets.

Cyndari Lab Members

Meet the Lab Members

Learn more about the Researchers that make up the Cyndari Lab!

Inflamed Knee Joint

About the Research

Learn more about the research that is done in the Cyndari Lab.

Welcoming

To trainees from diverse backgrounds and experiences

Partnership

Emergency Medicine, Immunology, Epidemiology

Novel

Human Based Tissue Assays

Lab in Hawaii

Cyndari Lab News

Check out the latest news and events happening in the Cyndari Laboratory!

Lab in Hawaii at Night

2025 American Association of Immunologists Conference

May 2025, Dr. Cyndari, KariAn Mulford, and KB Butler presented posters at the Annual Meeting of the American Association of Immunologists (AAI) in Honolulu, Hawaii.  Their presentations were entitled, "B. burgdorferi Infection Alters Synovial Macrophage Response in a Human ex vivo Model of Lyme Arthritis" and "The Effect of Infectious and inflammatory stimuli on the Synovium and Resident Synovial Macrophages in a Novel Human Explant Model."

2025 International Lyme Conference

2025 International Conference: Lyme Borreliosis

September 2025, Dr. Karen Cyndari and KariAn Mulford will present their work at the 2025 International Conference: Lyme Borreliosis and Other Tick-Borne Diseases. Their presentation is entitled, "B. burgdorferi Infection Alters Synovial Macrophage Response in a Human ex vivo Model of Lyme Arthritis."

Events

Biology Seminar: "Walking the razor's edge of life and death: New insights on compartmentalized neurodegeneration" promotional image

Biology Seminar: "Walking the razor's edge of life and death: New insights on compartmentalized neurodegeneration"

Friday, October 17, 2025 3:30pm
Biology Building East
The Department of Biology’s seminar speaker on Friday, Oct. 10, at 3:30 p.m. is from our own department, Dan Summers, an Assistant Professor. His seminar will be held in Kollros Auditorium (Room 101), Biology Building East (BBE). A reception with light refreshments will be held in the BBE Lobby following the seminar.

Department of Microbiology and Immunology Seminar Series

Tuesday, October 21, 2025 3:00pm to 4:00pm
Bowen Science Building
ACB Seminar Series - Julia von Blume  promotional image

ACB Seminar Series - Julia von Blume

Wednesday, October 22, 2025 9:30am to 10:30am
Bowen Science Building

Dr. Julia von Blume, an Associate Professor of Cell Biology from the Yale School of Medicine will present a seminar titled "Mechanism of Secretory Granule Biogenesis."

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