Cyndari Research Laboratory | The University of Iowa

University of Iowa Campus

Joint Space Immunology Laboratory

Understanding Immune System Regulation in the Joint Space to Improve Arthritis Outcomes

Emergency Medicine Immunology Inflammation Program

About the Joint Space Immunology Laboratory

Dr. Cyndari is an Emergency Medicine physician dedicated to improving outcomes for all her patients. The Cyndari Laboratory studies the immune response within the joint space during infectious and inflammatory arthritis. These studies implement a unique ex-vivo system using synovial tissue from human patients. This Joint Space Analysis system (JSAS) allows research in a human model to further understand the arthritic joint space and identify new potential treatment targets.

Meet the Lab Members

Learn more about the Researchers that make up the Cyndari Lab!

Our Funding

Learn more about the funding involved in helping us carry out our research!

About the Research

Learn more about the research that is done in the Cyndari Lab.

Welcoming

To trainees from diverse backgrounds and experiences

Partnership

Emergency Medicine, Immunology, Epidemiology

Novel

Human Based Tissue Assays

Cyndari Lab News

Check out the latest news and events happening in the Cyndari Laboratory!

Hanna Huston Presented a Poster at AAI 2026

Hanna Huston presented a poster at AAI 2026 in Boston, MA on April 15th, 2026. The title of her poster was CD163+ Tumor-Associated Macrophages and the Immune Microenvironment in Synovial Sarcoma Morphologies.

Hanna Huston Presented at WISC

Hanna Huston presented a talk and a poster at the 2026 WISC meeting held in Iowa City on April 10, 2026. She presented her work on the impact of the morphology of synovial sarcomas on the survivability outcomes.

AAI Equity in Immunology Travel Award

Hanna Huston received the American Association of Immunologists Equity in Immunology Travel Award to attend the AAI Annual Meeting in Boston, April 15-19, 2026. There she will present her work on iron cycling in the synovial sarcoma tumor microenvironment.

KariAn and Hanna Presented at EM Research Day 2026

KariAn Mulford and Hanna Huston presented their work at EM Research Day 2026 at the University of Iowa on April 30, 2026. KariAn presented her work on the effects of Lyme Arthritis on the synovial lining. Hanna presented her work on the impact of synovial sarcoma morphologies on the immune microenvironment.

Publications

Pinned

A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture

Wednesday, March 11, 2026

JoVE Journal

Pinned

Resident Synovial Macrophages in Synovial Fluid: Implications for Immunoregulation.

Tuesday, December 17, 2024

Clinical Immunology

Tick-borne coinfections modulate CD8+ T cell response and progressive leishmaniosis.

Tuesday, August 5, 2025

Infect Immun.

Events

Women In Micro & Immuno Coffee Hour

Monday, May 11, 2026 11:00am to 12:00pm

Carver Biomedical Research Building

Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion!

This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science.

Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.

Seminar Series: Department of Microbiology and Immunology

Tuesday, May 12, 2026 3:00pm to 4:00pm

Bowen Science Building

Each semester, we are proud to host outstanding seminar speakers. Everyone is encouraged to attend.

Microbiology Gradation Reception

Friday, May 15, 2026 3:00pm to 5:00pm

Eckstein Medical Research Building

Celebrate your incredible achievement! Bring family and friends to meet Microbiology Faculty, Staff, and Peers. Snacks and refreshments will be provided. This is the time to celebrate and take photos. (Optional: bring your regalia)

Home